Butyrophenones are neuroleptics used in schizophrenia patients, alcoholic delirium, senile psychosis, organic psychosis and some neurologic disorders. These neuroleptics block Dopamine receptors in the Central Nervous System. The most known Butyrophenones is “Haloperidol“.
Butyrophenones compared with Phenotiazines cause less hypo-tension, anticholinergic effects, cardiac complications, and sedation. However Haloperidol induces chronic cholestatic and more extra-pyramidal effects than other antipsychotic drugs.
(Edited by María Moya Guirao, M.D.)