Posts Tagged Under: Phenothiazines

Inhibited Orgasm

Inhibited Orgasm

Inhibited Orgasm

Inhibited Orgasm, also called Retarded Ejaculation, is a phenomena in which intravaginal ejaculation does not occur. In other cases there is also inability to masturbate to ejaculation .

The ethiology may be:

Psychological. Psychic factors cause most cases.

Organic. Eg. in Diabetes Mellitus.

Drugs. Eg. by some Phenothiazines.

Psychotherapy is indicated for Inhibited Orgasm caused by Psychic factors.


(Edited by Dr. María Moya Guirao, MD)

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Tardive Dyskinesia and Phenothiazines

Did you know that…..

the Phenothiazines may produce Tardive Dyskinesia ?

This adverse effect is characterized by choreiform movements of the buccal, lingual and fascial muscles. Sometimes may be also choreiform movements in the extremities.

Tardive Dyskinesia may be caused by high doses of Phenothiazines given over a long time.

Phenothiazines produce Tardive Dyskinesia in older patients, having normal doses.

(Edited by Dr. María Moya Guirao, MD)

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Phenothiazines are antipsychotic drugs. There are three important subgroups :

1– Aliphatics : Triflupromazine and Chlorpromazine (the most known).

2– Piperidine : Mesoridazine and Thioridazine.

3– Piperazine : Fluphenazine, Perphenazine, Prochlorperazine, and Triffluperazine.

The Phenothiazines are effective in acute and chronic schizophrenia, and do not produce drug dependence.

They have a marked effect on thought disturbances associated with paranoid ideation, deluxions, anxiety, and agitation.

Adverse effects are drowsiness, tardive dyskinesia, sedation, hypotension, extrapyramidal symptoms (eg, akathisia, dystonia,tremors, and rigidity), ocular and skin pigmentation, photosensitization, hepatotoxicity, and blood dyscrasias.

Phenothiazines may produce also arrhythmias, suppression of ovulation, and induction of lactation.

(Edited by Dr. María Moya Guirao, MD)

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